产品货号：
Z24155
中文名称：
PSEN2抗体
英文名称：
Anti-PSEN2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PSEN2 Antibody |
| 指标别名 | presenilin 2;AD3L;AD4;CMD1V;PS2;STM2;PSEN2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rabbit,rat |
| 应用范围 | WB,IHC |
| 基因名称 | PSEN2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human Presenilin 2(39-51aa EDGENTAQWRSQE),different from the related mouse and rat sequences by two amino acids. |
| 实际分子量 | 34KD(cleaved)/50KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Presenilin-2 is a protein that in humans is encoded by the PSEN2 gene.Kovacs et al.(1996) demonstrated that the expression patterns of PS1 and PS2 in the brain are extremely similar to each other and that messages for both are primarily detectable in neuronal populations.Immunochemical analyses indicated that PS1 and PS2 are similar in size and localize to similar intracellular compartments(endoplasmic reticulum and Golgi complex).Li et al.(1997) demonstrated that wildtype PS1 and PS2 are localized to the nuclear membrane,its associated interphase kinetochores,and the centrosomes.In melanocytic cells PSEN2 gene expression may be regulated by MITF. |
| Uniprot ID | P49810 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | presenilin 2(Alzheimer disease 4) |
| 蛋白名全称 | Presenilin-2(PS-2) |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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